A plethora of genetic, dietary, and pharmacological interventions can extend healthy lifespan in laboratory animals and can delay or ameliorate diverse aging-related diseases. Mechanisms of aging are conserved in evolution, and discoveries made in animals are informing our understanding of human aging. This raises the intriguing possibility of performing preventative medicine against chronic and age-related diseases, by targeting their main risk factor, namely aging. Important current challenges in the field are (1) to understand the downstream pathways by which longevity interventions can combat age-related loss of function and pathology, (2) to evaluate the impact of regenerative interventions and cellular reprogramming on age-related diseases, and (3) to translate the findings into the extension of human health span.
This fourth meeting will continue to explore these topics, with particular emphasis on what we can learn from variation in the rate of ageing in the natural world, mitochondria, cellular senescence, biomarkers and epidemiology, immune aging and reprogramming and rejuvenation strategies.
- Mitochondrial quality control and aging
- Autophagy and proteostasis
- Regenerative interventions and cellular reprogramming
- Human ageing: biomarkers and cell senescence
Confirmed Plenary Speakers
Yves Barral (ETH Zurich)
AGEING AND REJUVENATION: LESSONS FROM AN OLD FUNGAL FRIEND
Ivan Dikic (Goethe University)
ER-PHAGY NETWORKS AND AGING
Nils Goran Larsson (Karolinska Institutet)
METABOLIC CONSEQUENCES OF INHIBITION OF MITOCHONDRIAL TRANSCRIPTION
Joan Mannick (Life Biosciences)
DEVELOPING THERAPIES TO IMPROVE ANTIVIRAL IMMUNITY IN OLDER ADULTS
Masayo Takahashi (Vision Care Inc.)
RETINAL CELL THERAPY USING iPS CELLS
Confirmed Invited Speakers
Joris Deelen (Max Planck Institute for Biology of Ageing, Cologne)
IDENTIFICATION AND FUNCTIONAL CHARACTERISATION OF GENETIC VARIANTS LINKED TO HUMAN LONGEVITY
Robin Franklin (University of Cambridge)
MYELIN REGNERATION IN THE CNS: REVERSING THE RAVAGES OF TIME
Judith Frydman (Stanford University)
Martin Graef (Max Planck Institute for Biology of Ageing, Cologne)
MECHANISMS OF AUTOPHAGY AND CELLULAR AGEING
Cole Haynes (University of Massachusetts)
RE-ESTABLISHING (OR MAINTAINING) THE MITOCHONDRIAL NETWORK IN AGING CELLS
Brian Kennedy (National University of Singapore)
INCREASING THE INTERVENTION POOL TO EXTEND HEALTHSPAN
Joana Neves (University of Lisbon)
MOLECULAR AND CELLULAR MECHANISMS OF IMMUNE REJUVENATION IN TISSUE REPAIR
Tom Reh (University of Washington)
STUDYING AGING IN FETAL DEVELOPMENT
Pedro Sousa-Victor (University of Lisbon)
REGULATION OF INFLAMMATION TO IMPROVE REGENERATIVE CAPACITY WITH AGING
Thaddeus Stappenbeck (Cleveland Clinic Lerner Research Institute)
HUMAN VARIATION IN INTESTINAL EPITHELIAL STEM CELLS IN RESPONSE TO INFLAMMATORY CONDITIONS SUCH AS AGING, IBD AND OBESITY
Claire J. Steves (Kings College London)
GEROSCIENCE UNDERPINNING MULTI-MORBIDITY: EVIDENCE FROM TWINSUK AND UKBIOBANK
Please send talk and poster abstract submissions via email to the Conference Manager, Chloe. The oral and poster deadlines are noted above. We advise early submission to avoid disappointment due to limited slots.
- Basic scientists in the field of aging research using animal models.
- Human researchers interested in biomarkers of aging.
- Clinical trials specialists in aging and associated diseases.
- Scientists and other professionals developing aging interventions.
- Investors looking to enter this new space.
- Educated public.
The aging field encompasses a wide range of biology, involving many model organisms and, with respect to mammals, the involvement of many tissues. In addition, translational strategies to modify the rate of aging range from lifestyle change to drugs and, more recently stem cell-based therapeutics. As such, there is an abiding need to bring together scientists across diverse fields with the purpose of providing a clear overview of the state of basic research in aging and the development of translational strategies. The goal is to create cross-fertilization between scientists in different areas, accelerating the development of interventions that extend human health span.
We offer two price options for our virtual conferences. Please see below for details. If you register for a conference via our website, credit card payment is required. If you would prefer to pay via bank transfer, please contact us for an alternative registration method.
Standard Registration Fee: £217
This price grants access to the virtual conference for one user. Please note, your account is designed for single use. If another user tries to log into your account to access the virtual conference at the same time, the original user will be logged out immediately.
Lab Package Registration Fee: £500
This price grants access to the virtual conference for three users from the same lab. Please contact us if you are interested in this package for further details.
We have complimentary registrations available for postdocs and students. Please submit an abstract for talk or poster consideration via email to Chloe, along with a short message outlining why you would benefit from attending this conference. Applications must be submitted by 10th August 2021 for consideration.
Please note refunds can only be issued within 14 days of booking. Outside of this, all registration fees are non-refundable. Please see our Terms and Conditions for further details.
We have complimentary registrations available for postdocs and students. Please submit an abstract for poster consideration via email to Chloe, along with a short message outlining why you would benefit from attending this conference. Applications must be submitted by 18 September 2021 for consideration.